When suspecting a central nervous system lesion it is important to assess different facets of sensory integration. For example, light touch, two-point discrimination, temperature discrimination, sharp/blunt, kinaesthesia, proprioception, and stereognosis. When suspecting a peripheral nerve lesion however, it is more important to understand the difference between dermatomal and cutaneous nerve distributions. The purpose of this blog is to review aspects of sensory testing for a peripheral nerve lesion and differentiation from central nervous system lesions.